Emergence of the acute-phase protein hemopexin in jawed vertebrates
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چکیده
منابع مشابه
Emergence of the acute-phase protein hemopexin in jawed vertebrates.
When released from damaged erythrocytes free heme not only provides a source of iron for invading bacteria but also highly toxic due to its ability to catalyze free radical formation. Hemopexin (Hx) binds free heme with very high-affinity and thus protects against heme toxicity, sequesters heme from pathogens, and helps conserve valuable iron. Hx is also an acute-phase serum protein (APP), whos...
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Heterogeneous Conservation of Dlx Paralog Co-Expression in Jawed Vertebrates
BACKGROUND The Dlx gene family encodes transcription factors involved in the development of a wide variety of morphological innovations that first evolved at the origins of vertebrates or of the jawed vertebrates. This gene family expanded with the two rounds of genome duplications that occurred before jawed vertebrates diversified. It includes at least three bigene pairs sharing conserved regu...
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ژورنال
عنوان ژورنال: Molecular Immunology
سال: 2010
ISSN: 0161-5890
DOI: 10.1016/j.molimm.2010.08.015